Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL28389404 | 1.00 | CA5A (0.47) | CA5ACA5BLMNAALDH1A1TDP1 | |
| Nitric Acid SCHEMBL442180 | 1.00 | CA5A (0.47) | CA5ACA5BLMNAALDH1A1TDP1 | |
| Methacrylic Acid SCHEMBL27588163 | 0.82 | CA5A (0.32) | CA5ACA5BLMNA | |
| Nitric Acid SCHEMBL6858001 | 0.82 | CA5A (0.32) | CA5ACA5BLMNA | |
| Nitric Acid SCHEMBL5538160 | 0.82 | CA5A (0.47) | CA5ACA5BLMNAALDH1A1TDP1 | |
| SCHEMBL1079284 | 0.81 | LMNA (0.42) | LMNAALDH1A1TDP1TSHR | |
| Deanol SCHEMBL11140865 | 0.80 | CA5A (0.44) | CA5ACA5BLMNAALDH1A1TDP1 | |
| Nitric Acid SCHEMBL8606303 | 0.79 | CA5A (0.33) | CA5ACA5BLMNA | |
| Nitric Acid SCHEMBL10587822 | 0.79 | ALDH1A1 (0.48) | CA5ACA5BLMNAALDH1A1 | |
| SCHEMBL18403612 | 0.78 | LMNA (0.39) | LMNAALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457791-A | N,N'-DIMETHYL METHYLENE DINITRAMINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1984-07-03 | — | — | US | disclosed |