Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181389 | 0.85 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL8779347 | 0.82 | RAB9A (0.63) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL10878301 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL8779354 | 0.79 | RAB9A (0.59) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL9086956 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL19370459 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL2455112 | 0.77 | CA1 (0.41) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL3612969 | 0.76 | SMN1; SMN2 (0.76) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A | |
| SCHEMBL629408 | 0.75 | CA1 (0.62) | SMN1; SMN2CYP1A2RAB9AGLSKMT2A | |
| SCHEMBL8779364 | 0.75 | SMN1; SMN2 (0.79) | SMN1; SMN2CYP1A2HTTCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |