Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 6/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113767 | 0.90 | GAA (0.59) | KMT2AHTR1ASMN1; SMN2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11007073 | 0.89 | GAA (0.59) | KMT2AHTR1ADRD2DRD4DRD3 | |
| SCHEMBL11118598 | 0.87 | KMT2A (0.53) | KMT2AHTR1ADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11014416 | 0.83 | KMT2A (0.60) | KMT2AHTR1ASLC6A4USP2 | |
| SCHEMBL11010053 | 0.82 | DRD4 (0.64) | KMT2AHTR1ADRD2DRD4SLC6A4 | |
| SCHEMBL7882947 | 0.82 | HTR1A (0.69) | HTR1ASLC6A4 | |
| SCHEMBL8691170 | 0.82 | HTR1A (0.69) | HTR1ASLC6A4 | |
| SCHEMBL8695826 | 0.81 | HTR1A (0.70) | HTR1ASLC6A4 | |
| SCHEMBL7885543 | 0.81 | HTR1A (0.70) | HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL11015770 | 0.80 | LMNA (0.64) | KMT2AHTR1ASMN1; SMN2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112191-A1 | 4-(1H-indolyl-3-)-alpha-methyl piperidine-1-ethanol derivatives, their salts, process for their preparation, compositions containing them and their use as medicines | ROUSSEL-UCLAF (FR) | 1984-06-27 | — | — | EP | disclosed |