Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GPR183 | P32249 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516144 | 0.86 | MAPT (0.82) | MAPTALDH1A1GAAUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL68316 | 0.84 | MAPT (0.79) | MAPTALDH1A1GAAUSP2SMN1; SMN2 | |
| SCHEMBL5648270 | 0.83 | KMT2A (0.68) | MAPTALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL8802892 | 0.82 | ALDH1A1 (0.48) | MAPTFAAHALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6578765 | 0.81 | FAAH (0.62) | MAPTFAAHALDH1A1GAAHPGD | |
| SCHEMBL27965232 | 0.81 | ALDH1A1 (0.66) | MAPTFAAHALDH1A1GAAUSP2 | |
| SCHEMBL19380613 | 0.80 | MAPT (1.00) | MAPTFAAHSMN1; SMN2KMT2AFKBP1A | |
| SCHEMBL13234921 | 0.80 | MAPT (0.71) | MAPTFAAHALDH1A1GAAHPGD | |
| SCHEMBL19612588 | 0.80 | FAAH (1.00) | FAAH | |
| SCHEMBL31499420 | 0.79 | SMN1; SMN2 (0.79) | MAPTALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115413-A1 | +/- 2-(Phenethyl)-5-((3,4-methylenedioxy)-alpha-hydroxybenzyl)-pyrrolidines, pharmaceutical compositions containing them, processes for their production and intermediates therefor | SYNTEX (U.S.A.) INC. (US) | 1984-08-08 | — | — | EP | disclosed |