Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618234 | 0.89 | ALDH1A1 (0.58) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL29655855 | 0.84 | ALDH1A1 (0.62) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL6192070 | 0.84 | ALDH1A1 (0.62) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL26116950 | 0.84 | ALDH1A1 (0.67) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL1508924 | 0.84 | ALDH1A1 (0.62) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL7645545 | 0.82 | ALDH1A1 (0.60) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL7645547 | 0.82 | ALDH1A1 (0.60) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL4822306 | 0.81 | CYP3A4 (0.48) | ALDH1A1POLBCYP3A4HPGDTDP1 | |
| SCHEMBL6717590 | 0.80 | ALDH1A1 (1.00) | ALDH1A1POLBCYP3A4HPGDHSD17B10 | |
| SCHEMBL31618218 | 0.78 | ALDH1A1 (0.48) | ALDH1A1POLBCYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450159-A | ORGAN TRANSPLANTS; IMMUNOLOGY | THE UPJOHN COMPANY (US) | 1984-05-22 | — | — | US | disclosed |
| US-4352929-A | ANTIBODY INHIBITORS | THE UPJOHN COMPANY (US) | 1982-10-05 | — | — | US | disclosed |