Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAD1 | O60671 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508924 | 0.98 | ALDH1A1 (0.62) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL29655855 | 0.98 | ALDH1A1 (0.62) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL6114392 | 0.84 | ALDH1A1 (0.50) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL11117613 | 0.82 | ALDH1A1 (0.66) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL5897520 | 0.82 | ALDH1A1 (0.49) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| Sulfuric Acid SCHEMBL8443293 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL8678321 | 0.81 | CYP3A4 (0.45) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL28378340 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL3905753 | 0.80 | CYP1A2 (0.52) | ALDH1A1POLBRAD1P2RY6CYP1A2 | |
| SCHEMBL6192070 | 0.79 | ALDH1A1 (0.62) | ALDH1A1POLBCYP1A2ABCB11NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002060867-A2 | CARBAZOLE DERIVATIVES AND THEIR USES AS HEPARANASE INHIBITORS | INSIGHT STRATEGY AND MARKETING LTD (IL) | 2002-08-08 | — | — | WO | disclosed |