Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.59 |
| ▸ | CA1 | P00915 | 11/20 | 0.59 |
| ▸ | CA9 | Q16790 | 9/20 | 0.59 |
| ▸ | CA12 | O43570 | 6/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153928 | 0.84 | GAA (0.52) | CA2CA1CA9CA12CA4 | |
| SCHEMBL10422850 | 0.84 | ALDH1A1 (0.55) | CA2CA1CA9CA12CA4 | |
| SCHEMBL21550448 | 0.83 | ALDH1A1 (0.48) | CA2CA1CA9CA12CA4 | |
| SCHEMBL1803937 | 0.83 | PTGS1 (0.66) | CA2CA1CA9CA12CA4 | |
| SCHEMBL793608 | 0.82 | CA2 (0.69) | CA2CA1CA9CA12CA4 | |
| SCHEMBL5520735 | 0.79 | CA2 (0.68) | CA2CA1CA9CA12CA4 | |
| SCHEMBL1186046 | 0.78 | CA2 (0.70) | CA2CA1CA9CA12CA4 | |
| Clofenamide SCHEMBL310408 | 0.78 | CA1 (0.59) | CA2CA1CA9CA12CA4 | |
| SCHEMBL5805029 | 0.78 | CA2 (0.61) | CA2CA1CA9CA12CA4 | |
| Clofenamide SCHEMBL30748198 | 0.78 | CA1 (0.59) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129478-A2 | 2-Sulfamoylbenzo (b) thiophene derivatives, their preparation and pharmaceutical composition for the treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | disclosed |