Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857894 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL11115154 | 0.82 | GAA (0.46) | ALDH1A1TSHRHPGDALOX15MEN1 | |
| SCHEMBL11117131 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRHPGDALOX15MEN1 | |
| SCHEMBL9858075 | 0.82 | CYP2C19 (0.48) | ALDH1A1TSHRALOX15MEN1KMT2A | |
| SCHEMBL9858043 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL9857893 | 0.78 | CA5A (0.40) | ALDH1A1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL9858303 | 0.77 | PTGER1 (0.41) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL9857981 | 0.77 | HTT (0.39) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL10667959 | 0.76 | GAA (0.50) | ALDH1A1TSHRHPGDALOX15MEN1 | |
| SCHEMBL10667210 | 0.76 | GAA (0.47) | ALDH1A1TSHRHPGDALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114347-A2 | Aralkyl-triazole compounds | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |