Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857893 | 0.92 | CA5A (0.40) | CYP2C19ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9857894 | 0.82 | ALDH1A1 (0.43) | CYP2C19ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL11117769 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9858043 | 0.82 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL9858303 | 0.77 | PTGER1 (0.41) | ALDH1A1KMT2AMEN1TDP1MAPT | |
| SCHEMBL10664757 | 0.76 | NPSR1 (0.57) | CYP2C19ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9857981 | 0.75 | HTT (0.39) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL9857903 | 0.69 | CA5A (0.46) | CYP2C19ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL11010308 | 0.68 | CA5A (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2ATM | |
| SCHEMBL10670780 | 0.66 | TP53 (0.58) | ALDH1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199262-B1 | FLUORINATED BENZYL TRIAZOLE COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-02-27 | — | — | EP | disclosed |
| EP-0199262-A2 | Fluorinated benzyl triazole compounds | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |