Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40439 | 0.78 | ALDH1A1 (0.53) | MAPTALDH1A1HPGDCYP2D6KMT2A | |
| SCHEMBL9390740 | 0.75 | ALDH1A1 (0.50) | MAPTALDH1A1HPGDCYP2D6KMT2A | |
| SCHEMBL20005701 | 0.68 | MAPT (0.55) | MAPTMAPK1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11082747 | 0.66 | KMT2A (0.48) | MAPTALDH1A1HPGDCYP2D6KMT2A | |
| SCHEMBL1795649 | 0.65 | ALDH1A1 (0.50) | MAPTMAPK1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL717117 | 0.65 | ALDH1A1 (0.50) | MAPTMAPK1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3817361 | 0.65 | ALDH1A1 (0.50) | MAPTMAPK1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL9742723 | 0.65 | CYP2D6 (0.48) | MAPK1ALDH1A1HPGDKDM4ECYP2D6 | |
| SCHEMBL16118505 | 0.65 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDCYP2D6KMT2A | |
| SCHEMBL5164869 | 0.65 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDCYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450159-A | ORGAN TRANSPLANTS; IMMUNOLOGY | THE UPJOHN COMPANY (US) | 1984-05-22 | — | — | US | claimed |