SCHEMBL5164869

SCHEMBL5164869

CC(c1ccccc1)N1C(=O)COC1=O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
CYP2D6 P10635 2/20 0.44
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.41
HSD11B1 P28845 2/20 0.40
MC4R P32245 1/20 0.40
ALOX12 P18054 1/20 0.39
FAAH O00519 1/20 0.38
NR3C2 P08235 2/20 0.38
USP1 O94782 1/20 0.37
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16118505 1.00 ALDH1A1 (0.46) ALDH1A1HPGDCYP2D6MAPTKMT2A
SCHEMBL16118510 0.83 HSD11B1 (0.43) HSD11B1NR3C2
SCHEMBL16118611 0.82 THRB (0.40) MAPTKMT2ANR3C2
SCHEMBL16118607 0.80 HSD11B1 (0.46) MAPTHSD11B1NR3C2POLB
SCHEMBL16118554 0.79 HSD11B1 (0.44) ALDH1A1KMT2AHSD11B1ALOX12NR3C2
SCHEMBL16118590 0.78 CREBBP (0.42) NR3C2
SCHEMBL40439 0.76 ALDH1A1 (0.53) ALDH1A1HPGDCYP2D6MAPTKMT2A
SCHEMBL3625929 0.74 CHRM1 (0.34) ALDH1A1KMT2AALOX12FAAHCYP2C19
SCHEMBL27378016 0.74 ALDH1A1 (0.40) ALDH1A1HPGDCYP2D6MAPTKMT2A
SCHEMBL9390740 0.73 ALDH1A1 (0.50) ALDH1A1HPGDCYP2D6MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7267925-B2 Photosensitive composition and novel compound used therefor FUJIFILM CORPORATION (JP) 2007-09-11 US disclosed
EP-1471387-A2 Photosensitive composition and compound used thereof FUJI PHOTO FILM CO., LTD. (JP) 2004-10-27 EP disclosed
US-20040191679-A1 Photosensitive composition and novel compound used therefor FUJI PHOTO FILM CO., LTD. 2004-09-30 US disclosed