SCHEMBL1795649

SCHEMBL1795649

C[C@H](c1ccccc1)N1C(=O)C=CC1=O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
CYP2D6 P10635 2/20 0.48
MAPT P10636 2/20 0.43
MC4R P32245 1/20 0.42
MGLL Q99685 3/20 0.41
CYP2C19 P33261 1/20 0.41
FAAH O00519 2/20 0.41
KMT2A Q03164 2/20 0.40
MET P08581 1/20 0.40
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
CASP1 P29466 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717117 1.00 ALDH1A1 (0.50) ALDH1A1HPGDCYP2D6MAPTMC4R
SCHEMBL3817361 1.00 ALDH1A1 (0.50) ALDH1A1HPGDCYP2D6MAPTMC4R
SCHEMBL32665606 0.79 ESR1 (0.46) ALDH1A1HPGDCYP2D6MAPTMGLL
SCHEMBL19371518 0.79 MGLL (0.45) MGLLFAAHKMT2AMEN1
SCHEMBL32665283 0.79 ESR1 (0.46) ALDH1A1HPGDCYP2D6MAPTMGLL
SCHEMBL384411 0.77 MGLL (0.44) ALDH1A1HPGDCYP2D6MGLLFAAH
SCHEMBL2175411 0.77 MGLL (0.44) ALDH1A1HPGDCYP2D6MAPTMGLL
SCHEMBL607042 0.77 LMNA (0.58) ALDH1A1HPGDCYP2D6LMNA
SCHEMBL6925572 0.77 LMNA (0.58) ALDH1A1HPGDCYP2D6LMNA
SCHEMBL29393294 0.77 LMNA (0.58) ALDH1A1HPGDCYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220241730-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR RENSSELAER POLYTECHNIC INSTITUTE (US) 2022-08-04 US claimed
US-11154819-B2 Anti-fouling chiral surfaces for membrane filtration and methods therefor RENSSELAER POLYTECHNIC INSTITUTE (US) 2021-10-26 US claimed
US-20200197874-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR RENSSELAER POLYTECHNIC INSTITUTE (US) 2020-06-25 US claimed
US-10453420-B2 Base film, laminated structure including the same, and display device LG CHEM, LTD. (KR) 2019-10-22 US claimed
US-20170189857-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR RENSSELAER POLYTECHNIC INSTITUTE (US) 2017-07-06 US claimed
US-20150299841-A1 BASE FILM, LAMINATED STRUCTURE INCLUDING THE SAME, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2015-10-22 US claimed
US-11712665-B2 Anti-fouling chiral surfaces for membrane filtration and methods therefor RENSSELAER POLYTECHNIC INSTITUTE (US) 2023-08-01 US disclosed
US-20220241730-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR RENSSELAER POLYTECHNIC INSTITUTE (US) 2022-08-04 US disclosed
US-11154819-B2 Anti-fouling chiral surfaces for membrane filtration and methods therefor RENSSELAER POLYTECHNIC INSTITUTE (US) 2021-10-26 US disclosed
US-20200197874-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR RENSSELAER POLYTECHNIC INSTITUTE (US) 2020-06-25 US disclosed
US-10453420-B2 Base film, laminated structure including the same, and display device LG CHEM, LTD. (KR) 2019-10-22 US disclosed
US-20170189857-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR RENSSELAER POLYTECHNIC INSTITUTE (US) 2017-07-06 US disclosed
WO-2016007615-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR BELFORT GEORGES (US) 2016-01-14 WO disclosed
US-6712971-B2 ANIONIC POLYMERIZATION OF (S)-(-)-N-ALPHA-METHYLBENZYL MALEIMIDE IN THE PRESENCE OF AN ASYMMETRIC LIGAND; HIGH SPECIFIC ROTATION AND MOLECULAR WEIGHT TOSOH CORPORATION (JP) 2004-03-30 US disclosed
US-20040030073-A1 Optically active poly (N-methylbenzylmaleimide), method for its production and its use TOSOH CORPORATION 2004-02-12 US disclosed
WO-2004004665-A2 SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD BRISTOL-MYERS SQUIBB COMPANY (US) 2004-01-15 WO disclosed
US-20030149221-A1 Anionic polymerization of (S)-(-)-N-alpha-methylbenzyl maleimide in the presence of an asymmetric ligand; high specific rotation and molecular weight TOSOH CORPORATION 2003-08-07 US disclosed
US-6509478-B2 Having a specific rotation (( alpha )43525) of at least +30 degrees. TOSOH CORPORATION (JP) 2003-01-21 US disclosed
US-20020061994-A1 Optically active poly (N-methylbenzylmaleimide), method for its production and its use TOSOH CORPORATION (JP) 2002-05-23 US disclosed
EP-1191043-A1 Separating medium, method for its production and its use Tosoh Corporation (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11712665-B2 Anti-fouling chiral surfaces for membrane filtration and methods therefor ICAM1, EPCAM, SLC46A1 ALDH1A1 634/4885HPGD 3914/4885CYP2D6 1308/4885
US-20200197874-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR ICAM1, EPCAM, SLC46A1 ALDH1A1 634/4885HPGD 3914/4885CYP2D6 1308/4885
US-11154819-B2 Anti-fouling chiral surfaces for membrane filtration and methods therefor ICAM1, EPCAM, SLC46A1 ALDH1A1 634/4885HPGD 3914/4885CYP2D6 1308/4885
US-20220241730-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR ICAM1, EPCAM, SLC46A1 ALDH1A1 634/4885HPGD 3914/4885CYP2D6 1308/4885
US-20170189857-A1 ANTI-FOULING CHIRAL SURFACES FOR MEMBRANE FILTRATION AND METHODS THEREFOR ICAM1, EPCAM, SLC46A1 ALDH1A1 634/4885HPGD 3914/4885CYP2D6 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.