Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768277 | 0.91 | SHBG (0.57) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL11169807 | 0.82 | ALDH1A1 (0.53) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL14369343 | 0.82 | ESR1 (0.52) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL8606013 | 0.82 | SHBG (0.55) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL30702410 | 0.82 | SHBG (0.55) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL27776956 | 0.79 | RORC (0.47) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL716558 | 0.78 | CYP3A4 (0.42) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL14369344 | 0.77 | SHBG (0.58) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL4629051 | 0.77 | SHBG (0.57) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL10981747 | 0.76 | SHBG (0.52) | CYP3A4CYP2D6HIF1ASHBGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049166-B1 | HYDROLYTICALLY STABLE DIPHOSPHITES USEFUL AS ANTIOXIDANTS | UNIROYAL, INC. (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4384062-A | Hydrolytically stable diphosphites useful as antioxidants | UNIROYAL, INC. (US) | 1983-05-17 | — | — | US | disclosed |
| US-4341721-A | ANTIOXIDANT | UNIROYAL, INC. (US) | 1982-07-27 | — | — | US | disclosed |
| EP-0049166-A1 | Hydrolytically stable diphosphites useful as antioxidants | UNIROYAL, INC. (US) | 1982-04-07 | — | — | EP | disclosed |