Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | ENO1 | P06733 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147193 | 0.79 | TDP1 (0.46) | TDP1MEN1LMNAHPGDTSHR | |
| SCHEMBL14617621 | 0.77 | TDP1 (0.43) | TDP1MEN1LMNAHPGDTSHR | |
| SCHEMBL25284521 | 0.75 | MMP1 (0.33) | TDP1ALDH1A1MMP1MMP8 | |
| SCHEMBL263667 | 0.70 | LAP3 (0.42) | TDP1MEN1LMNAHPGDTSHR | |
| SCHEMBL2974723 | 0.67 | FDPS (0.57) | LAP3 | |
| SCHEMBL9003816 | 0.67 | GRIN2D (0.46) | TDP1MEN1LMNAHPGDTSHR | |
| SCHEMBL7941318 | 0.67 | BLM (0.47) | TDP1MEN1LMNAHPGDTSHR | |
| SCHEMBL2994534 | 0.67 | FDPS (0.50) | TDP1MEN1LMNAHPGDTSHR | |
| SCHEMBL28728326 | 0.67 | MEN1 (0.43) | TDP1MEN1LMNAHPGDTSHR | |
| SCHEMBL7836561 | 0.65 | MEN1 (0.37) | TDP1MEN1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121117-A1 | Derivatives of dihydropyridine and production thereof | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-10-10 | — | — | EP | disclosed |