Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124428 | 0.87 | ALDH1A1 (0.47) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL23240110 | 0.82 | SMARCA2 (0.50) | RAB9AALDH1A1MAPTNPC1MEN1 | |
| SCHEMBL11120354 | 0.81 | RAB9A (0.52) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL11120996 | 0.79 | RAB9A (0.47) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL8304223 | 0.78 | ALDH1A1 (0.53) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL11120485 | 0.77 | FAAH (0.48) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL11123083 | 0.77 | ALDH1A1 (0.55) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL11119518 | 0.76 | CCNE1 (0.47) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL11116697 | 0.76 | ALDH1A1 (0.48) | RAB9AALDH1A1MAPTNPC1PKM | |
| SCHEMBL11120441 | 0.74 | RAB9A (0.45) | RAB9AALDH1A1MAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129408-A2 | (3-alkyl-5-isothiazolyl)ureas | ELI LILLY AND COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |