Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475165 | 0.83 | TAAR1 (0.52) | MAOBMAOA | |
| SCHEMBL3421201 | 0.76 | LMNA (0.85) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL10609652 | 0.75 | LMNA (0.75) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL339813 | 0.75 | LMNA (0.82) | LTA4HEPHX2BCHEMAOBLMNA | |
| SCHEMBL12040562 | 0.74 | LTA4H (0.77) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL5599 | 0.74 | LTA4H (0.66) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL12630258 | 0.74 | LTA4H (0.77) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL11117749 | 0.73 | HRH4 (0.49) | LTA4HHRH3L3MBTL1 | |
| SCHEMBL1699213 | 0.73 | LTA4H (0.64) | LTA4HEPHX2FFAR1FFAR4BCHE | |
| SCHEMBL3940420 | 0.73 | LTA4H (0.64) | LTA4HEPHX2FFAR1FFAR4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115413-A1 | +/- 2-(Phenethyl)-5-((3,4-methylenedioxy)-alpha-hydroxybenzyl)-pyrrolidines, pharmaceutical compositions containing them, processes for their production and intermediates therefor | SYNTEX (U.S.A.) INC. (US) | 1984-08-08 | — | — | EP | disclosed |