Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714735 | 0.87 | HRH3 (0.55) | DAOMAOAMAOBGPR84 | |
| SCHEMBL4350635 | 0.87 | HRH3 (0.50) | DAOMAOA | |
| SCHEMBL7172295 | 0.85 | MAOA (0.42) | DAOMAOA | |
| SCHEMBL17104827 | 0.85 | HRH3 (0.53) | DAOMAOAGPR84 | |
| SCHEMBL11118375 | 0.83 | LTA4H (0.54) | MAOAMAOB | |
| SCHEMBL1108477 | 0.79 | TAAR1 (0.50) | TAAR1DAOMAOAHPGD | |
| SCHEMBL11117749 | 0.77 | HRH4 (0.49) | ALDH1A1 | |
| SCHEMBL9410203 | 0.76 | MAOA (0.41) | TAAR1DAOMAOAMAOBALDH1A1 | |
| SCHEMBL7003873 | 0.75 | GPR84 (0.41) | DAOMAOAGPR84 | |
| SCHEMBL9203304 | 0.75 | DAO (0.51) | TAAR1DAOMAOAMAOBGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112194629-A | Phenethyl azole derivative and preparation method and application thereof | 聊城大学 | 2021-01-08 | — | — | CN | claimed |
| CN-104203918-B | Novel polymorphic crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the beta2 adrenergic receptor. | 阿尔米雷尔有限公司 | 2017-01-18 | — | — | CN | claimed |
| CN-112194629-B | Phenethyl azole derivative and preparation method and application thereof | 聊城大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-112194629-B | Phenethyl azole derivative and preparation method and application thereof | 聊城大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-112194629-B | Phenethyl azole derivative and preparation method and application thereof | 聊城大学 | 2023-10-24 | — | — | CN | disclosed |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS | 2022-01-27 | — | — | US | disclosed |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2021-04-13 | — | — | US | disclosed |
| CN-112194629-A | Phenethyl azole derivative and preparation method and application thereof | 聊城大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-112194629-A | Phenethyl azole derivative and preparation method and application thereof | 聊城大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-112194629-A | Phenethyl azole derivative and preparation method and application thereof | 聊城大学 | 2021-01-08 | — | — | CN | disclosed |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2020-03-05 | — | — | US | disclosed |
| US-9873697-B2 | Histone demethylase inhibitors | Celgene Quantical Research, Inc. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20170313702-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-11-02 | — | — | US | disclosed |
| EP-1001933-A4 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1001933-A1 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006367-A1 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0611301-A1 | CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0611301-A4 | CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS. | PROCTER & GAMBLE (US) | 1993-03-01 | — | — | EP | disclosed |
| WO-1991016034-A1 | CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
| EP-0115413-A1 | +/- 2-(Phenethyl)-5-((3,4-methylenedioxy)-alpha-hydroxybenzyl)-pyrrolidines, pharmaceutical compositions containing them, processes for their production and intermediates therefor | SYNTEX (U.S.A.) INC. (US) | 1984-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313702-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5A | TAAR1 4275/4885DAO 2300/4885MAOA 537/4885 |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | TAAR1 2540/4885DAO 4189/4885MAOA 4630/4885 |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | TAAR1 2540/4885DAO 4189/4885MAOA 4630/4885 |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | GRPR, HSP90B1, HSPE1 | TAAR1 2540/4885DAO 4189/4885MAOA 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.