Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL11149081 | 0.88 | TSHR (0.45) | MAPK1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL10580550 | 0.86 | MAPK1 (0.52) | MAPK1TSHRALDH1A1VCAM1TDP1 | |
| Nitrophenolate SCHEMBL11130646 | 0.76 | KCNMA1 (0.51) | MAPK1TSHRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11050246 | 0.75 | ALDH1A1 (0.43) | MAPK1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL11050240 | 0.74 | TSHR (0.47) | MAPK1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL1524058 | 0.74 | MAPK1 (0.72) | MAPK1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL10957067 | 0.73 | TSHR (0.46) | MAPK1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL3138248 | 0.73 | MAPK1 (0.64) | MAPK1TSHRALDH1A1LMNAPOLB | |
| SCHEMBL914901 | 0.73 | ALDH1A1 (0.48) | TSHRALDH1A1TDP1GPR35 | |
| SCHEMBL31688378 | 0.73 | ALDH1A1 (0.48) | TSHRALDH1A1TDP1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043801-B1 | 2-SUBSTITUTED 5-PHENOXY-PHENYL-PHOSPHINIC-ACID DERIVATIVES WITH HERBICIDAL ACTIVITY, PROCESS FOR PREPARING THEM, HERBICIDAL COMPOSITIONS CONTAINING THEM AND USE OF THESE ACTIVE SUBSTANCES AND COMPOSITIONS | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | disclosed |