Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230620 | 0.85 | TSHR (0.52) | ALDH1A1MEN1KMT2AKDM4EFLT1 | |
| SCHEMBL25765618 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL10850438 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3919635 | 0.83 | GSK3B (0.55) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL1144066 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29712843 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29115419 | 0.81 | POLB (0.47) | ALDH1A1KMT2ASMN1; SMN2HSP90AB1MAPK1 | |
| SCHEMBL6331423 | 0.81 | HSP90AB1 (0.67) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8688272 | 0.80 | HTT (0.62) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL581464 | 0.80 | HSD11B1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660991-A | Antiproliferative compounds and methods of use thereof | 细胞基因公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-100395234-C | Novel CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2008-06-18 | — | — | CN | disclosed |
| CN-101012193-A | Novel CB 1 receptour inverse agonists | HOFFMANN LA ROCHE (CH) | 2007-08-08 | — | — | CN | disclosed |
| CN-1735593-A | Novel CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2006-02-15 | — | — | CN | disclosed |
| EP-0107198-A1 | Use of 2-hydroxy-2-methyl-(p-chloropropionphenone) as a photoinitiator | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |