Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 6/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185179 | 0.73 | RYR2 (0.36) | RYR2HSD17B3NOTUMKMT2ASIGMAR1 | |
| SCHEMBL17043256 | 0.73 | RYR2 (0.36) | RYR2HSD17B3NOTUMKMT2ASIGMAR1 | |
| SCHEMBL31146716 | 0.73 | RYR2 (0.36) | RYR2HSD17B3NOTUMKMT2ASIGMAR1 | |
| SCHEMBL6969929 | 0.73 | RYR2 (0.40) | RYR2HSD17B3NOTUMKMT2ASIGMAR1 | |
| SCHEMBL17185647 | 0.73 | RYR2 (0.36) | RYR2HSD17B3NOTUMKMT2ASIGMAR1 | |
| SCHEMBL3894929 | 0.73 | RYR2 (0.36) | RYR2HSD17B3NOTUMKMT2ASIGMAR1 | |
| SCHEMBL29463396 | 0.73 | MAOA (0.40) | RYR2HSD17B3NOTUMSIGMAR1MAOA | |
| SCHEMBL19674181 | 0.73 | RYR2 (0.40) | RYR2HSD17B3NOTUMKMT2ASIGMAR1 | |
| SCHEMBL11217635 | 0.73 | MAOA (0.40) | RYR2HSD17B3NOTUMSIGMAR1MAOA | |
| SCHEMBL27357854 | 0.72 | RYR2 (0.44) | RYR2HSD17B3NOTUMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039483-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-BENZOTHIAZOLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | claimed |
| EP-0039483-A1 | Process for the preparation of 2-hydroxy-benzothiazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-11 | — | — | EP | claimed |
| EP-0039483-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-BENZOTHIAZOLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | disclosed |
| EP-0039483-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-BENZOTHIAZOLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | disclosed |
| EP-0039483-A1 | Process for the preparation of 2-hydroxy-benzothiazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-11 | — | — | EP | disclosed |
| EP-0039483-A1 | Process for the preparation of 2-hydroxy-benzothiazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-11 | — | — | EP | disclosed |
| EP-0039483-A1 | Process for the preparation of 2-hydroxy-benzothiazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-11 | — | — | EP | disclosed |