Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 6/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185179 | 0.73 | RYR2 (0.36) | RYR2HSD17B3RXFP1NOTUMKMT2A | |
| SCHEMBL29463396 | 0.73 | MAOA (0.40) | RYR2HSD17B3NOTUMALDH1A1HPGD | |
| SCHEMBL11118465 | 0.73 | RYR2 (0.40) | RYR2HSD17B3RXFP1NOTUMKMT2A | |
| SCHEMBL17043256 | 0.73 | RYR2 (0.36) | RYR2HSD17B3RXFP1NOTUMKMT2A | |
| SCHEMBL31146716 | 0.73 | RYR2 (0.36) | RYR2HSD17B3RXFP1NOTUMKMT2A | |
| SCHEMBL17185647 | 0.73 | RYR2 (0.36) | RYR2HSD17B3RXFP1NOTUMKMT2A | |
| SCHEMBL3894929 | 0.73 | RYR2 (0.36) | RYR2HSD17B3RXFP1NOTUMKMT2A | |
| SCHEMBL19674181 | 0.73 | RYR2 (0.40) | RYR2HSD17B3RXFP1NOTUMKMT2A | |
| SCHEMBL11217635 | 0.73 | MAOA (0.40) | RYR2HSD17B3NOTUMALDH1A1HPGD | |
| SCHEMBL8521754 | 0.72 | RYR2 (0.37) | RYR2HSD17B3RXFP1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5716974-A | TREATING FUNGAL PLANT DISEASES | ISAGRO S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | disclosed |