Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173910 | 0.89 | MEN1 (0.53) | FABP4FABP5CXCL8MEN1KMT2A | |
| SCHEMBL11119661 | 0.87 | SLC6A4 (0.50) | CHRM1FABP4FABP5CXCL8MEN1 | |
| SCHEMBL872958 | 0.83 | CXCL8 (0.67) | CHRM1PPARAFABP4FABP5CXCL8 | |
| SCHEMBL11120421 | 0.82 | CXCL8 (0.71) | CHRM1FABP4FABP5CXCL8MEN1 | |
| SCHEMBL11121989 | 0.82 | CHRM1 (0.51) | CHRM1PPARAFABP4FABP5CXCL8 | |
| Ammonia Solution, Strong SCHEMBL872909 | 0.81 | CHRM1 (0.65) | CHRM1PPARAFABP4FABP5CXCL8 | |
| SCHEMBL29639215 | 0.81 | KMT2A (0.54) | FABP4FABP5MEN1KMT2ANPC1 | |
| SCHEMBL991380 | 0.81 | KMT2A (0.54) | FABP4FABP5MEN1KMT2ANPC1 | |
| SCHEMBL11121247 | 0.80 | HTT (0.51) | CHRM1FABP4FABP5CXCL8POLB | |
| SCHEMBL11123672 | 0.80 | SLC6A4 (0.50) | PPARAPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033614-B1 | PHENYLALKANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-06 | — | — | EP | disclosed |
| US-4367238-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| EP-0033614-A1 | Phenylalkanoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-12 | — | — | EP | disclosed |