Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL872909 | 0.98 | CHRM1 (0.65) | CXCL8CHRM1PPARAHTR2ASLC6A4 | |
| SCHEMBL838629 | 0.88 | CAMK2A (0.68) | CXCL8CHRM1PPARASLC6A4SLC6A2 | |
| SCHEMBL966658 | 0.87 | PPARA (0.57) | CXCL8CHRM1PPARAHTR2ASLC6A4 | |
| Hydrogen Sulfide SCHEMBL28780977 | 0.86 | CAMK2A (0.66) | CXCL8CHRM1PPARASLC6A4SLC6A2 | |
| SCHEMBL11121989 | 0.86 | CHRM1 (0.51) | CXCL8CHRM1PPARAHTR2ASLC6A4 | |
| SCHEMBL872781 | 0.86 | CHRM1 (0.52) | CXCL8CHRM1PPARAHTR2ASLC6A4 | |
| SCHEMBL11335218 | 0.85 | CXCL8 (0.59) | CXCL8CHRM1CAMK2AFFAR1ALDH1A1 | |
| SCHEMBL10561756 | 0.85 | CXCL8 (0.69) | CXCL8CHRM1PPARAHTR2ASLC6A4 | |
| SCHEMBL2353783 | 0.85 | CAMK2A (0.69) | CXCL8CHRM1PPARACAMK2AFFAR1 | |
| SCHEMBL11574819 | 0.84 | CHRM1 (0.58) | CXCL8CHRM1PPARAHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038975-A2 | PROCESS FOR THE PREPARATION OF (3ARS,12BRS)-5-CHLORO-2-METHYL-2,3,3A12B-TETRAHYDRO-1HDIBENZO[2,3:6,7] OXEPINO [4,5-C]PYRROLE MALEATE AND IT'S PHARMACEUTICAL COMPOSITION THEREOF | MSN LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| EP-2520176-B1 | Method for increasing the nutritional value of rapeseed and rape products with decreased oil content | ROP REPCE OLAJ PELLET KFT (HU) | 2019-02-20 | — | — | EP | disclosed |
| EP-2468751-B1 | Processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole | MEDICHEM SA (ES) | 2016-03-16 | — | — | EP | disclosed |
| EP-2468751-B1 | Processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole | MEDICHEM SA (ES) | 2016-03-16 | — | — | EP | disclosed |
| US-8921359-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921359-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921359-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| EP-2324032-B1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS INC (US) | 2014-10-01 | — | — | EP | disclosed |
| EP-2324032-B1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS INC (US) | 2014-10-01 | — | — | EP | disclosed |
| US-8779161-B2 | Asenapine maleate | DR. REDDY'S LABORATORIES LIMITED (IN) | 2014-07-15 | — | — | US | disclosed |
| EP-1710241-A1 | Intermediate compounds for the prepation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1h-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole | Organon Ireland Ltd. (IE) | 2006-10-11 | — | — | EP | disclosed |
| US-20060154954-A1 | Combinations and use of selected pharmaceutically active compounds | ALTANA PHARMA AG (DE) | 2006-07-13 | — | — | US | disclosed |
| EP-0556381-B1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOW AGROSCIENCES LLC (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0555469-A4 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0556381-A4 | — | DOWELANCO (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5399564-A | N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides | DOWELANCO (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0556381-A1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOWELANCO (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0555469-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1993004580-A1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |
| WO-1993005050-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES_________________ | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |