Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.65 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.54 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872958 | 0.98 | CXCL8 (0.67) | CHRM1CXCL8PPARAHTR2ASLC6A4 | |
| SCHEMBL838629 | 0.87 | CAMK2A (0.68) | CHRM1CXCL8PPARASLC6A4SLC6A2 | |
| SCHEMBL966658 | 0.86 | PPARA (0.57) | CHRM1CXCL8PPARAHTR2ASLC6A4 | |
| Hydrogen Sulfide SCHEMBL28780977 | 0.85 | CAMK2A (0.66) | CHRM1CXCL8PPARASLC6A4SLC6A2 | |
| SCHEMBL11121989 | 0.85 | CHRM1 (0.51) | CHRM1CXCL8PPARAHTR2ASLC6A4 | |
| SCHEMBL872781 | 0.85 | CHRM1 (0.52) | CHRM1CXCL8PPARAHTR2ASLC6A4 | |
| SCHEMBL11335218 | 0.84 | CXCL8 (0.59) | CHRM1CXCL8CAMK2AFFAR1ALDH1A1 | |
| SCHEMBL2353783 | 0.84 | CAMK2A (0.69) | CHRM1CXCL8PPARACAMK2AFFAR1 | |
| SCHEMBL10561756 | 0.84 | CXCL8 (0.69) | CHRM1CXCL8PPARAHTR2ASLC6A4 | |
| SCHEMBL2555874 | 0.83 | CXCL8 (0.58) | CHRM1CXCL8PPARASLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038975-A2 | PROCESS FOR THE PREPARATION OF (3ARS,12BRS)-5-CHLORO-2-METHYL-2,3,3A12B-TETRAHYDRO-1HDIBENZO[2,3:6,7] OXEPINO [4,5-C]PYRROLE MALEATE AND IT'S PHARMACEUTICAL COMPOSITION THEREOF | MSN LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |