Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120686 | 0.88 | ALDH1A1 (0.42) | ARSLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL11125776 | 0.84 | CXCL8 (0.42) | ARSLC6A2SLC6A4SLC6A3ABCB1 | |
| SCHEMBL11125167 | 0.84 | SLC6A2 (0.47) | ARSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL11173106 | 0.84 | MEN1 (0.44) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL4160051 | 0.82 | SMN1; SMN2 (0.46) | TSHRMEN1KMT2ASMN1; SMN2ABCB1 | |
| SCHEMBL8595893 | 0.82 | ABCB1 (0.43) | SLC6A2SLC6A4SLC6A3TSHRMEN1 | |
| SCHEMBL22904150 | 0.81 | AR (0.44) | ARSLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL11126341 | 0.80 | AR (0.40) | ARSCN8ATSHRMEN1NPC1 | |
| SCHEMBL11125447 | 0.80 | AR (0.40) | ARSLC6A2SLC6A4SLC6A3SCN8A | |
| SCHEMBL1235279 | 0.80 | SGMS2 (0.42) | SCN8ATSHRNPC1RAB9AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033614-B1 | PHENYLALKANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-06 | — | — | EP | disclosed |
| US-4367238-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| EP-0033614-A1 | Phenylalkanoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-12 | — | — | EP | disclosed |