Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | DDX3X | O00571 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631293 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL730213 | 0.83 | MAPT (0.62) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL29689011 | 0.82 | KMT2A (0.61) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL5880840 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL28211599 | 0.79 | MAPT (0.57) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL28807504 | 0.79 | MAPT (0.62) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL11124580 | 0.79 | MAPT (0.71) | SMN1; SMN2MAPTKMT2AMEN1POLB | |
| SCHEMBL8975021 | 0.79 | MAPT (0.57) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL868793 | 0.79 | KMT2A (0.55) | SMN1; SMN2MAPTKMT2AMEN1DDX3X | |
| SCHEMBL12932901 | 0.79 | KMT2A (0.56) | SMN1; SMN2MAPTKMT2AMEN1DDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030846-B1 | PHARMACOLOGICALLY ACTIVE PEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELI LILLY AND COMPANY (US) | 1984-05-09 | — | — | EP | disclosed |
| EP-0030846-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4251439-A | ENKEPHALIN ANALOGS AS ANALGESICS | ELI LILLY AND COMPANY (US) | 1981-02-17 | — | — | US | disclosed |