Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.65 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444883 | 0.84 | PLA2G1B (0.60) | PLA2G1BPOLBATG4BPNMTSIGMAR1 | |
| SCHEMBL9241138 | 0.83 | PLA2G1B (0.58) | PLA2G1BPOLBATG4BPNMTSIGMAR1 | |
| SCHEMBL17894815 | 0.82 | PNMT (0.51) | PLA2G1BPOLBATG4BPNMTSIGMAR1 | |
| SCHEMBL17892844 | 0.82 | PNMT (0.51) | PLA2G1BPOLBATG4BPNMTSIGMAR1 | |
| SCHEMBL9858988 | 0.81 | HTR1A (0.52) | PLA2G1BPOLBATG4BSIGMAR1FPR2 | |
| SCHEMBL6003758 | 0.80 | FPR2 (0.51) | PLA2G1BPOLBATG4BPNMTFPR2 | |
| SCHEMBL6005718 | 0.80 | FPR2 (0.51) | PLA2G1BPOLBATG4BPNMTFPR2 | |
| SCHEMBL6005310 | 0.80 | FPR2 (0.51) | PLA2G1BPOLBATG4BPNMTFPR2 | |
| Ammonia Solution, Strong SCHEMBL5311103 | 0.79 | PNMT (0.56) | PLA2G1BPOLBATG4BPNMTSIGMAR1 | |
| SCHEMBL25343509 | 0.79 | SMO (0.53) | PLA2G1BPOLBATG4BSMOSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028305-B1 | DIARYL COMPOUNDS AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| EP-0028305-A1 | Diaryl compounds and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-05-13 | — | — | EP | disclosed |