Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.50 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490525 | 1.00 | PAX8 (0.58) | PAX8HPGDLMNATP53GMNN | |
| SCHEMBL28637076 | 0.90 | PAX8 (0.47) | PAX8HPGDLMNATP53GMNN | |
| SCHEMBL18490404 | 0.90 | PAX8 (0.47) | PAX8HPGDLMNATP53GMNN | |
| SCHEMBL27216191 | 0.90 | PAX8 (0.47) | PAX8HPGDLMNATP53GMNN | |
| SCHEMBL22577506 | 0.90 | PAX8 (0.47) | PAX8HPGDLMNATP53GMNN | |
| SCHEMBL25680068 | 0.89 | PAX8 (0.47) | PAX8HPGDSMN1; SMN2 | |
| SCHEMBL11122063 | 0.86 | ADORA2A (0.50) | PAX8HPGDLMNATP53DPP4 | |
| SCHEMBL9347293 | 0.86 | ADORA2A (0.50) | PAX8HPGDLMNATP53DPP4 | |
| SCHEMBL11122756 | 0.84 | P2RX3 (0.60) | ADORA1SMN1; SMN2ATIC | |
| SCHEMBL25680062 | 0.84 | STING1 (0.42) | PAX8HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043722-B1 | BETA-D-ARABINOFURANOSYLIMIDAZO (4,5-C)PYRIDINE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1984-05-23 | — | — | EP | claimed |
| US-4315000-A | β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-02-09 | — | — | US | claimed |
| EP-0043722-A1 | Beta-D-Arabinofuranosylimidazo (4,5-c)pyridine compounds and processes for their production | WARNER-LAMBERT COMPANY (US) | 1982-01-13 | — | — | EP | claimed |
| EP-0043722-B1 | BETA-D-ARABINOFURANOSYLIMIDAZO (4,5-C)PYRIDINE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |
| US-4315000-A | β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-02-09 | — | — | US | disclosed |
| EP-0043722-A1 | Beta-D-Arabinofuranosylimidazo (4,5-c)pyridine compounds and processes for their production | WARNER-LAMBERT COMPANY (US) | 1982-01-13 | — | — | EP | disclosed |