Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490404 | 1.00 | PAX8 (0.47) | PAX8HPGDSTING1LMNAGMNN | |
| SCHEMBL27216191 | 1.00 | PAX8 (0.47) | PAX8HPGDSTING1LMNAGMNN | |
| SCHEMBL22577506 | 1.00 | PAX8 (0.47) | PAX8HPGDSTING1LMNAGMNN | |
| SCHEMBL18510819 | 0.90 | STING1 (0.41) | PAX8HPGDSTING1GSK3ARPS6KA3 | |
| SCHEMBL25807922 | 0.90 | STING1 (0.41) | PAX8HPGDSTING1GSK3ARPS6KA3 | |
| SCHEMBL11123739 | 0.90 | PAX8 (0.58) | PAX8HPGDLMNAGMNNALDH1A1 | |
| SCHEMBL18490525 | 0.90 | PAX8 (0.58) | PAX8HPGDLMNAGMNNALDH1A1 | |
| SCHEMBL25680068 | 0.82 | PAX8 (0.47) | PAX8HPGDSTING1GSK3ARPS6KA3 | |
| SCHEMBL25680062 | 0.81 | STING1 (0.42) | PAX8HPGDSTING1GSK3ARPS6KA3 | |
| SCHEMBL22883167 | 0.81 | P2RX3 (0.59) | PAX8HPGDSTING1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694397-B | Cyclic dinucleotide compounds, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-08-31 | — | — | CN | disclosed |