SCHEMBL11123740

SCHEMBL11123740

CCOC(OCC)C(O)O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.42
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20581374 0.80 THRB (0.44) THRBLMNATSHR
SCHEMBL10571822 0.80 THRB (0.44) THRBLMNATSHR
SCHEMBL1568155 0.78 THRB (0.57) THRBLMNA
SCHEMBL7249527 0.78 LMNA (0.47) THRBLMNATSHR
SCHEMBL3108838 0.78 LMNA (0.47) THRBLMNATSHR
SCHEMBL2348928 0.75 THRB (0.40) THRBLMNATSHR
SCHEMBL8924726 0.75 THRB (0.40) THRBLMNATSHR
SCHEMBL1146477 0.75 THRB (0.40) THRBLMNATSHR
SCHEMBL19990186 0.75 THRB (0.40) THRBLMNATSHR
SCHEMBL16382093 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0063367-B1 ACETAL STABILIZED PROSTAGLANDIN COMPOSITIONS SYNTEX (U.S.A.) INC. (US) 1984-08-22 EP claimed