Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387219 | 0.78 | HSD17B10 (0.37) | — | |
| SCHEMBL9681077 | 0.76 | LMNA (0.39) | THRBLMNATSHR | |
| SCHEMBL17469360 | 0.75 | — | — | |
| SCHEMBL10571822 | 0.75 | THRB (0.44) | THRBLMNATSHR | |
| SCHEMBL20581374 | 0.75 | THRB (0.44) | THRBLMNATSHR | |
| SCHEMBL11123740 | 0.75 | THRB (0.44) | THRBLMNATSHR | |
| SCHEMBL27803885 | 0.75 | THRB (0.44) | THRBLMNA | |
| SCHEMBL5891559 | 0.75 | THRB (0.44) | THRBLMNA | |
| SCHEMBL7379274 | 0.74 | THRB (0.38) | THRBLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL1568155 | 0.73 | THRB (0.57) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622999-A | HEAT AND CHEMICAL RESISTANCE | POLINVENT FEJLESZTO, KIVITELEZO ES ERTEKESITO KFT (HU) | 1997-04-22 | — | — | US | claimed |
| US-5622999-A | HEAT AND CHEMICAL RESISTANCE | POLINVENT FEJLESZTO, KIVITELEZO ES ERTEKESITO KFT (HU) | 1997-04-22 | — | — | US | disclosed |