Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050733 | 0.92 | TSHR (0.51) | ALDH1A1KDM4ENPC1TSHRGAA | |
| SCHEMBL11047395 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPC1GAAMAPT | |
| SCHEMBL11047175 | 0.87 | GAA (0.57) | ALDH1A1KDM4ENPC1GAAMAPT | |
| SCHEMBL11123787 | 0.87 | LMNA (0.48) | LMNAALDH1A1KDM4ENPC1TSHR | |
| SCHEMBL11044864 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1GAAMAPT | |
| SCHEMBL10642523 | 0.86 | LMNA (0.47) | LMNAALDH1A1KDM4ENPC1TSHR | |
| SCHEMBL11045419 | 0.85 | LMNA (0.46) | LMNAALDH1A1KDM4ENPC1TSHR | |
| SCHEMBL11045450 | 0.85 | LMNA (0.49) | LMNAALDH1A1KDM4ENPC1TSHR | |
| SCHEMBL11047586 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1GAAMAPT | |
| SCHEMBL11044877 | 0.84 | LMNA (0.46) | LMNAALDH1A1KDM4ENPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |