Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12787335 | 0.81 | CA12 (0.48) | ALDH1A1METAP1ALDH2CA12CA9 | |
| SCHEMBL6906979 | 0.80 | MAOA (0.46) | ALDH1A1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL29372231 | 0.78 | ESR2 (0.44) | ALDH1A1KDM4EMEN1HPGDHTT | |
| SCHEMBL28470495 | 0.77 | CA2 (0.45) | ALDH1A1KDM4EHPGDMAOBMETAP1 | |
| SCHEMBL28889921 | 0.76 | MAOB (0.65) | ALDH1A1KDM4EMEN1HPGDHTT | |
| SCHEMBL57888 | 0.74 | MAOA (0.62) | ALDH1A1KDM4EHPGDMAOBMAOA | |
| SCHEMBL29800444 | 0.74 | MAOA (0.62) | ALDH1A1KDM4EHPGDMAOBMAOA | |
| SCHEMBL8638020 | 0.74 | CA12 (0.43) | ALDH1A1KDM4EMEN1HPGDHTT | |
| SCHEMBL13199306 | 0.73 | MAOA (0.45) | ALDH1A1KDM4EMEN1KMT2AMAOB | |
| SCHEMBL11577633 | 0.73 | PTGS1 (0.37) | ALDH1A1KDM4EMEN1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050396-B1 | COUMARIN INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-12-27 | — | — | EP | disclosed |