Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255941 | 0.83 | PLA2G2C (0.42) | PLA2G2CALDH1A1CA2CA1SIRT6 | |
| SCHEMBL3958639 | 0.80 | KDM4E (0.33) | PLA2G2CALDH1A1 | |
| SCHEMBL11129180 | 0.77 | PLA2G2C (0.40) | PLA2G2CALDH1A1CA2CA1SIRT6 | |
| SCHEMBL6547737 | 0.71 | PLA2G2C (0.62) | PLA2G2CCA2CA1PLA2G2A | |
| SCHEMBL2760205 | 0.70 | TAS1R3 (0.50) | PLA2G2CCA2CA1MAPK1 | |
| SCHEMBL10885085 | 0.69 | SIRT6 (0.46) | PLA2G2CALDH1A1CA2CA1SIRT6 | |
| SCHEMBL13525107 | 0.68 | SIRT6 (0.49) | PLA2G2CALDH1A1CA2CA1SIRT6 | |
| SCHEMBL20211076 | 0.68 | PLA2G2C (0.50) | PLA2G2CALDH1A1CA2CA1SIRT6 | |
| SCHEMBL11506429 | 0.68 | PLA2G2C (0.59) | PLA2G2CCA2CA1PLA2G2A | |
| SCHEMBL13715798 | 0.68 | PLA2G2C (0.59) | PLA2G2CCA2CA1MAPK1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487725-A | Process for the preparation of N-acetylaminoarylsulfonic acids in sulfuric acid as solvent | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-11 | — | — | US | disclosed |