Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124255 | 0.83 | PLA2G2C (0.41) | PLA2G2CSIRT6SIRT1CA2CA1 | |
| SCHEMBL346041 | 0.79 | KDM4E (0.34) | PLA2G2CRECQLCA2CA1MAPK1 | |
| SCHEMBL27662774 | 0.79 | ZDHHC20 (0.46) | TP53DPP7RECQLCA2CA1 | |
| SCHEMBL11129180 | 0.79 | PLA2G2C (0.40) | PLA2G2CSIRT6SIRT1TP53CA2 | |
| SCHEMBL11801865 | 0.74 | TP53 (0.42) | TP53DPP7CA2CA1ALDH1A1 | |
| Acetone SCHEMBL27726020 | 0.74 | ZDHHC20 (0.49) | PLA2G2CSIRT6SIRT1TP53MAPK1 | |
| SCHEMBL504372 | 0.74 | PAOX (0.33) | SIRT6SIRT1RECQLMAPK1ALDH1A1 | |
| Octane SCHEMBL28273512 | 0.73 | EPHX1 (0.46) | PLA2G2CSIRT6SIRT1TP53CA2 | |
| SCHEMBL1634618 | 0.73 | ZDHHC20 (0.51) | PLA2G2CTP53MAPK1EPHX1 | |
| SCHEMBL10627062 | 0.73 | ZDHHC20 (0.51) | PLA2G2CTP53MAPK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095177-A1 | Process for the preparation of N-acetylamino-aryl-sulphonic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-30 | — | — | EP | disclosed |