Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126954 | 0.90 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL2574478 | 0.85 | PTGS2 (0.43) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL11122647 | 0.82 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL11123963 | 0.78 | NPC1 (0.52) | RAB9ANPC1SMN1; SMN2PKMPOLB | |
| SCHEMBL11120007 | 0.76 | HPGD (0.51) | RAB9ASMN1; SMN2KMT2AHSD17B10MAPK1 | |
| SCHEMBL11122645 | 0.76 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL11126090 | 0.74 | HSD17B10 (0.44) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL11121125 | 0.74 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| Benzene SCHEMBL28149443 | 0.74 | HDAC3 (0.43) | NFKB1POLBALDH1A1TSHRKDM4E | |
| SCHEMBL19244157 | 0.74 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030350-B1 | METHOD FOR REDUCING THE TERMINAL CARBOXYL GROUP CONTENT OF A SATURATED POLYESTER, A SATURATED POLYESTER HAVING A REDUCED TERMINAL CARBOXYL GROUP CONTENT, AND A MOLDED ARTICLE COMPOSED OF SUCH A SATURATED POLYESTER | TEIJIN LIMITED (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4351936-A | COMPRISING ENDCAPPING WITH AN OXAZOLINE OR OXAZINE | TEIJIN LIMITED (JP) | 1982-09-28 | — | — | US | disclosed |
| EP-0030350-A1 | Method for reducing the terminal carboxyl group content of a saturated polyester, a saturated polyester having a reduced terminal carboxyl group content, and a molded article composed of such a saturated polyester | TEIJIN LIMITED (JP) | 1981-06-17 | — | — | EP | disclosed |