Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067433 | 0.81 | SLC6A3 (0.53) | SLC6A3SLC6A2ADRA1ASLC6A4HSD11B1 | |
| SCHEMBL29940424 | 0.81 | SLC6A3 (0.53) | SLC6A3SLC6A2ADRA1ASLC6A4HSD11B1 | |
| SCHEMBL4040088 | 0.80 | SLC18A3 (0.44) | ALDH1A1KDM4EKMT2ANR3C1 | |
| SCHEMBL7414530 | 0.80 | SLC18A3 (0.44) | ALDH1A1KDM4EKMT2ANR3C1 | |
| SCHEMBL3790814 | 0.74 | SLC6A3 (0.50) | MDM2SLC6A3SLC6A2ADRA1ASLC6A4 | |
| SCHEMBL3786501 | 0.74 | HDAC4 (0.52) | MDM2SLC6A3SLC6A2ADRA1ASLC6A4 | |
| SCHEMBL8178790 | 0.73 | ESR2 (0.47) | MDM2SLC6A3SLC6A2ADRA1ASLC6A4 | |
| SCHEMBL16233611 | 0.73 | SLC6A2 (0.46) | MDM2SLC6A3SLC6A2ADRA1AALDH1A1 | |
| SCHEMBL28947504 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL5983355 | 0.72 | SLC6A3 (0.43) | MDM2SLC6A3SLC6A2ADRA1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051211-B1 | USE OF CARBONIC-ACID/CARBAMIC-ACID ANHYDRIDES AS CO2-CLEAVING BLOWING AGENTS IN THE PRODUCTION OF CELLULAR OR FOAM-LIKE PLASTICS | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4377644-A | RIGID POLYURETHANES HAVING COMPACT SKINS | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0051211-A1 | Use of carbonic-acid/carbamic-acid anhydrides as CO2-cleaving blowing agents in the production of cellular or foam-like plastics | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |