Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307335 | 0.79 | ELANE (0.54) | TSHRALDH1A1HPGDCA12CA9 | |
| SCHEMBL7305862 | 0.73 | TSHR (0.63) | TSHRALDH1A1PKMLMNAHPGD | |
| SCHEMBL10567143 | 0.73 | TSHR (0.63) | TSHRALDH1A1PKMLMNAPOLB | |
| SCHEMBL10351658 | 0.73 | TSHR (0.68) | TSHRALDH1A1PKMPOLBHPGD | |
| SCHEMBL15720303 | 0.72 | TSHR (0.54) | TSHRALDH1A1LMNA | |
| SCHEMBL9557112 | 0.70 | TSHR (0.72) | TSHRALDH1A1POLBMAPK1 | |
| SCHEMBL2604740 | 0.69 | CA12 (0.58) | ALDH1A1PKMCA12CA9CASP3 | |
| SCHEMBL10814293 | 0.66 | ALDH1A1 (1.00) | TSHRALDH1A1PKMLMNAPOLB | |
| SCHEMBL11120445 | 0.65 | ALDH1A1 (0.68) | TSHRALDH1A1POLBGAASMN1; SMN2 | |
| SCHEMBL11843816 | 0.64 | CA12 (0.48) | ALDH1A1PKMCA12CA9CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056444-B1 | PHOTOGRAPHIC ELEMENTS CONTAINING BLOCKED PHOTOGRAPHIC REAGENTS AND PROCESSES EMPLOYING SAME | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-05-09 | — | — | EP | disclosed |
| US-4350752-A | Photographic elements and film units containing imidomethyl blocked photographic reagents | EASTMAN KODAK COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0056444-A2 | Photographic elements containing blocked photographic reagents and processes employing same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1982-07-28 | — | — | EP | disclosed |