SCHEMBL2604740

SCHEMBL2604740

O=C1c2ccccc2C(=O)N1CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.58
TGM2 P21980 1/20 0.58
CA9 Q16790 1/20 0.58
GLS O94925 1/20 0.58
ALDH1A1 P00352 2/20 0.54
CASP3 P42574 3/20 0.52
DRD3 P35462 1/20 0.50
MEN1 O00255 1/20 0.50
PKM P14618 1/20 0.50
KMT2A Q03164 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
GSK3B P49841 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11843816 0.84 CA12 (0.48) CA12TGM2CA9GLSALDH1A1
SCHEMBL6699936 0.83 GLS (0.71) CA12CA9GLSCASP3NPC1
SCHEMBL7287742 0.81 CA12 (0.56) CA12CA9GLSALDH1A1CASP3
SCHEMBL8586834 0.79 CA12 (0.54) CA12CA9GLSALDH1A1CASP3
SCHEMBL927806 0.79 CA12 (0.54) CA12CA9GLSALDH1A1CASP3
SCHEMBL1330864 0.79 CA12 (0.54) CA12CA9GLSALDH1A1CASP3
SCHEMBL31402 0.79 CA12 (0.54) CA12CA9GLSALDH1A1CASP3
SCHEMBL22890833 0.79 CA12 (0.54) CA12CA9GLSALDH1A1CASP3
SCHEMBL92102 0.79 CYP1B1 (0.67) CA12CA9GLSALDH1A1DRD3
SCHEMBL13065906 0.79 CA12 (0.54) CA12CA9GLSALDH1A1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688312-A INKS WITH COLORS AND IMIDES OR BISIMIDES, FOR ACOUSTIC INK PRINTER AND DROP EJECTOR XEROX CORPORATION (US) 1997-11-18 US claimed
CN-117222621-A Asymmetric methylenebisimides and their preparation 阿尔萨达股份公司 2023-12-12 CN disclosed
US-11746184-B2 Polyimide-polyarylene polymers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-05 US disclosed
US-11746254-B2 Tunable refractive index polymers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-05 US disclosed
US-20180134849-A1 POLYMER COMPOSITION AND STERILIZABLE ARTICLES OBTAINABLE THEREFROM SOLVAY SPECIALTY POLYMERS USA, LLC 2018-05-17 US disclosed
US-20160304716-A1 FRICTION AND WEAR RESISTANT ARTICLES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-10-20 US disclosed
US-9454077-B2 Photochemical methods and photoactive compounds for modifying surfaces THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-09-27 US disclosed
US-20160231649-A1 Photochemical Methods and Photoactive Compounds for Modifying Surfaces NATIONAL SCIENCE FOUNDATION 2016-08-11 US disclosed
US-9340691-B2 Hot melt ink composition comprising a copolyester and process for preparing a copolyester OCE-TECHNOLOGIES B.V. (NL) 2016-05-17 US disclosed
US-20160130441-A1 Reinforced compositions Solvay Special Polymers USA, LLC 2016-05-12 US disclosed
US-20080255309-A1 High-Performance Polysulfone Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2008-10-16 US disclosed
US-20080234440-A1 High-Performance Poly(Aryl Ether Sulfone) Composition SOLVAY ADVANCED PLOYMERS, L.L.C. (US) 2008-09-25 US disclosed
US-7396895-B2 Branched polyarylene ethers and processes for the preparation thereof XEROX CORPORATION (US) 2008-07-08 US disclosed
US-20080118853-A1 BRANCHED POLYARYLENE ETHERS AND PROCESSES FOR THE PREPARATION THEREOF XEROX CORPORATION (US) 2008-05-22 US disclosed
US-20070276100-A1 Electronic Components SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-11-29 US disclosed
US-5688312-A INKS WITH COLORS AND IMIDES OR BISIMIDES, FOR ACOUSTIC INK PRINTER AND DROP EJECTOR XEROX CORPORATION (US) 1997-11-18 US disclosed
EP-0156966-B1 WHOLLY AROMATIC POLYESTER COMPOSITION AND PROCESS FOR PRODUCING IT TEIJIN LIMITED (JP) 1988-10-19 EP disclosed
EP-0070539-B1 PROCESS FOR PRODUCING A FILM-LIKE AND FIBROUS ARTICLE OF A WHOLLY AROMATIC POLYESTER TEIJIN LIMITED (JP) 1987-07-01 EP disclosed
EP-0091669-B1 PROCESS FOR PRODUCING POROUS, FILM-LIKE OR FIBROUS STRUCTURE OF AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-10-01 EP disclosed
US-4517315-A Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1985-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746184-B2 Polyimide-polyarylene polymers PAICS, PIN1, PARN CA12 3584/4885TGM2 4364/4885CA9 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.