Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 6/20 | 0.67 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.52 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126472 | 1.00 | FCER2 (0.67) | FCER2MMP1MMECYP1A2CYP3A4 | |
| SCHEMBL8895703 | 0.92 | FCER2 (0.66) | FCER2MMP1MMEERAP2ERAP1 | |
| SCHEMBL8895697 | 0.92 | FCER2 (0.66) | FCER2MMP1MMEERAP2ERAP1 | |
| SCHEMBL8897334 | 0.91 | FCER2 (0.73) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8897345 | 0.91 | FCER2 (0.73) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL11124818 | 0.91 | MME (0.70) | FCER2MMECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7324192 | 0.91 | MME (0.70) | FCER2MMECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9556647 | 0.88 | FCER2 (0.67) | FCER2MMP1MMEERAP2ERAP1 | |
| SCHEMBL5870418 | 0.87 | BIRC2 (0.67) | FCER2MMECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10952133 | 0.87 | BIRC2 (0.67) | FCER2MMECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038046-B1 | PHARMACEUTICAL AMIDES, AND PREPARATION, FORMULATIONS AND USE THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-29 | — | — | EP | disclosed |
| EP-0038046-A2 | Pharmaceutical amides, and preparation, formulations and use thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-21 | — | — | EP | disclosed |