Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 8/20 | 0.73 |
| ▸ | MMP1 | P03956 | 6/20 | 0.67 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.58 |
| ▸ | MMP2 | P08253 | 4/20 | 0.54 |
| ▸ | MMP9 | P14780 | 4/20 | 0.54 |
| ▸ | MMP7 | P09237 | 3/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.52 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897345 | 1.00 | FCER2 (0.73) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8895703 | 0.94 | FCER2 (0.66) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8895697 | 0.94 | FCER2 (0.66) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8896488 | 0.91 | FCER2 (0.62) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8896480 | 0.91 | FCER2 (0.62) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL11126472 | 0.91 | FCER2 (0.67) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL11126476 | 0.91 | FCER2 (0.67) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL9068808 | 0.91 | MMP2 (0.65) | FCER2MMP2MMP9MMP7MMP12 | |
| SCHEMBL14272151 | 0.84 | MMP9 (0.59) | FCER2MMP1MMP2MMP9MMP7 | |
| SCHEMBL7324192 | 0.83 | MME (0.70) | FCER2MMP2MMP9MMP7MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686422-A | Synthetic inhibitors of mammalian collagenase | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0358660-B1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RES CORP TECHNOLOGIES INC (US) | 1994-05-25 | — | — | EP | disclosed |
| EP-0358660-A4 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | — | 1991-01-09 | — | — | EP | disclosed |
| EP-0358660-A1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE. | RES CORP TECHNOLOGIES INC (US) | 1990-03-21 | — | — | EP | disclosed |
| WO-1988006890-A1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-09-22 | — | — | WO | disclosed |