Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 7/20 | 0.66 |
| ▸ | MMP1 | P03956 | 4/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
| ▸ | MMP8 | P22894 | 3/20 | 0.52 |
| ▸ | MMP7 | P09237 | 3/20 | 0.52 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895697 | 1.00 | FCER2 (0.66) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8897334 | 0.94 | FCER2 (0.73) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8897345 | 0.94 | FCER2 (0.73) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8896488 | 0.93 | FCER2 (0.62) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8896480 | 0.93 | FCER2 (0.62) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL11126472 | 0.92 | FCER2 (0.67) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL11126476 | 0.92 | FCER2 (0.67) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL9068808 | 0.88 | MMP2 (0.65) | FCER2MMP2MMP9MMP7MME | |
| SCHEMBL8899095 | 0.84 | MME (0.68) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL8899092 | 0.84 | MME (0.68) | FCER2MMP1ERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686422-A | Synthetic inhibitors of mammalian collagenase | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0358660-B1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RES CORP TECHNOLOGIES INC (US) | 1994-05-25 | — | — | EP | disclosed |