Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 3/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839698 | 0.84 | AKR1C3 (0.62) | NPC1POLBCYP2C9RAB9ATNKS | |
| Ammonia Solution, Strong SCHEMBL11124803 | 0.83 | FFAR1 (0.50) | CYP2C9MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL4742580 | 0.80 | AKR1C3 (0.70) | NPC1POLBCYP2C9RAB9AMAOB | |
| SCHEMBL11128445 | 0.79 | NPC1 (0.49) | NPC1POLBCYP2C9RAB9AMAOB | |
| SCHEMBL5951864 | 0.76 | GSK3B (0.61) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL27491000 | 0.75 | HSD17B1 (0.56) | POLBTNKSPARP15PARP14PARP10 | |
| SCHEMBL11075350 | 0.75 | CES2 (0.55) | MAOBMAPK14AKR1C3NPSR1MRGPRX4 | |
| SCHEMBL11210510 | 0.74 | IDH1 (0.51) | NPC1POLBCYP2C9RAB9AMEN1 | |
| SCHEMBL11691009 | 0.74 | PARP10 (0.55) | NPC1POLBRAB9APARP10MAPT | |
| SCHEMBL11128497 | 0.73 | FFAR1 (0.50) | CYP2C9MEN1KMT2ANPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401602-A | PRE- AND POSTEMERGENCE HERBICIDES; DESICCANTS; DEFOLIATION; PLANT GROWTH REGULATORS | PPG INDUSTRIES, INC. (US) | 1983-08-30 | — | — | US | disclosed |
| US-4344789-A | Acids and esters of 5-(2-optionally substituted-4-trifluoromethyl-6-optionally substituted phenoxy)-2-nitro, -halo, or-cyano alpha substituted phenyl carboxy oximes, and method of controlling weeds with them | PPG INDUSTRIES, INC. (US) | 1982-08-17 | — | — | US | disclosed |