Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.50 |
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14873909 | 0.93 | EPHX1 (0.56) | EPHX1NAAACASP2 | |
| SCHEMBL14873911 | 0.91 | EPHX1 (0.59) | EPHX1NAAACASP2 | |
| SCHEMBL14873846 | 0.91 | EPHX1 (0.59) | EPHX1NAAACASP2 | |
| SCHEMBL14873864 | 0.91 | EPHX1 (0.59) | EPHX1NAAACASP2 | |
| SCHEMBL6360789 | 0.88 | — | — | |
| SCHEMBL9165872 | 0.80 | EPHX1 (0.48) | EPHX1ACHEMMP2NAAATSHR | |
| SCHEMBL4160606 | 0.80 | EPHX1 (0.48) | EPHX1ACHEMMP2NAAATSHR | |
| SCHEMBL8950824 | 0.80 | EPHX1 (0.48) | EPHX1ACHEMMP2NAAATSHR | |
| SCHEMBL29306458 | 0.80 | KDM4E (0.34) | EPHX1NAAA | |
| SCHEMBL8950790 | 0.80 | EPHX1 (0.48) | EPHX1ACHEMMP2NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034326-B1 | CHIRAL POLYSILOXANES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Bayer, Ernst, Prof. Dr. (DE) | 1984-07-25 | — | — | EP | claimed |
| US-10285986-B2 | Compounds and anti-tumor NQO1 substrates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-05-14 | — | — | US | disclosed |
| US-20180207150-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-07-26 | — | — | US | disclosed |
| US-20180207150-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-07-26 | — | — | US | disclosed |
| EP-2768308-B1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | UNIV ILLINOIS (US) | 2018-04-18 | — | — | EP | disclosed |
| US-9925180-B2 | Compounds and anti-tumor NQO1 substrates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-27 | — | — | US | disclosed |
| US-9925180-B2 | Compounds and anti-tumor NQO1 substrates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-27 | — | — | US | disclosed |
| US-20170182030-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170182030-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-06-29 | — | — | US | disclosed |
| US-9611266-B2 | Compounds and anti-tumor NQO1 substrates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-04-04 | — | — | US | disclosed |
| US-9611266-B2 | Compounds and anti-tumor NQO1 substrates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-04-04 | — | — | US | disclosed |
| US-20160122348-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160122348-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-05 | — | — | US | disclosed |
| US-9233960-B2 | Compounds and anti-tumor NQO1 substrates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233960-B2 | Compounds and anti-tumor NQO1 substrates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-12 | — | — | US | disclosed |
| US-20150011509-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLNOIS (US) | 2015-01-08 | — | — | US | disclosed |
| US-20150011509-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLNOIS (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2013056073-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011509-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | NQO1, KEAP1, SDHA | EPHX1 1343/4885ACHE 4483/4885MMP2 1397/4885 |
| US-20160122348-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | NQO1, KEAP1, SDHA | EPHX1 1314/4885ACHE 4414/4885MMP2 1395/4885 |
| US-20180207150-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | NQO1, KEAP1, SDHA | EPHX1 1204/4885ACHE 4352/4885MMP2 1720/4885 |
| US-10285986-B2 | Compounds and anti-tumor NQO1 substrates | NQO1, KEAP1, SDHA | EPHX1 1204/4885ACHE 4352/4885MMP2 1720/4885 |
| US-20170182030-A1 | COMPOUNDS AND ANTI-TUMOR NQO1 SUBSTRATES | NQO1, KEAP1, SDHA | EPHX1 1204/4885ACHE 4352/4885MMP2 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.