Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139007 | 0.93 | EPHX2 (0.46) | CYP4A11CYP4F2HRH1HTR2AMAOA | |
| SCHEMBL11131179 | 0.87 | CYP4A11 (0.62) | CYP4A11CYP4F2HRH1HTR2AMAOA | |
| SCHEMBL11132203 | 0.86 | HDAC8 (0.46) | HDAC1 | |
| SCHEMBL26517824 | 0.86 | TAAR1 (0.52) | CYP4A11CYP4F2ADRB2ADRB1F2RL1 | |
| SCHEMBL27357681 | 0.85 | FAAH (0.55) | — | |
| SCHEMBL26239880 | 0.85 | FAAH (0.55) | — | |
| SCHEMBL7824247 | 0.85 | FFAR1 (0.54) | HDAC1 | |
| SCHEMBL9673644 | 0.85 | CYP4A11 (0.63) | CYP4A11CYP4F2ADRB2ADRB1F2RL1 | |
| Hydrochloric Acid SCHEMBL9265296 | 0.84 | TAAR1 (0.50) | CYP4A11CYP4F2ADRB2ADRB1F2RL1 | |
| SCHEMBL11133301 | 0.84 | PTGER2 (0.45) | CYP4A11CYP4F2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-B1 | AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |
| EP-0044541-A1 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds | TEIJIN LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |