Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11131194 | 0.86 | CYP4A11 (0.45) | HDAC1 | |
| SCHEMBL11134922 | 0.86 | CYP4F2 (0.56) | NPC1MAPTLMNAL3MBTL1THRA | |
| Hydrochloric Acid SCHEMBL11136891 | 0.85 | CYP4F2 (0.55) | NPC1MAPTLMNAL3MBTL1THRA | |
| Acetamide SCHEMBL11133913 | 0.83 | HSD17B3 (0.51) | THRATHRBHSD17B3 | |
| SCHEMBL11137178 | 0.83 | THRA (0.44) | HDAC8HDAC1MAPTLMNAL3MBTL1 | |
| SCHEMBL11133895 | 0.82 | SMN1; SMN2 (0.47) | HDAC8HDAC1NPC1RAB9AMAPT | |
| SCHEMBL11130533 | 0.82 | SMN1; SMN2 (0.47) | HDAC8HDAC1NPC1RAB9AMAPT | |
| SCHEMBL11135374 | 0.82 | DPP4 (0.46) | HDAC8HDAC1NPC1RAB9AMAPT | |
| SCHEMBL11134216 | 0.82 | HDAC3 (0.54) | HDAC8HDAC1NPC1RAB9AMAPT | |
| SCHEMBL11134102 | 0.82 | HDAC3 (0.54) | HDAC8HDAC1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-B1 | AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |