Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 5/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136070 | 0.99 | ADRB2 (0.44) | PTGER2ADRB2ADRB1PTGER4PTGER3 | |
| SCHEMBL11131896 | 0.87 | CYP4F2 (0.54) | CPB2PPARGF2CYP4F2CYP4A11 | |
| SCHEMBL11136082 | 0.86 | CYP4F2 (0.46) | PTGER2PTGER4PTGER3CYP4F2CYP4A11 | |
| SCHEMBL11131194 | 0.84 | CYP4A11 (0.45) | ADRB2ADRB1CYP4F2CYP4A11 | |
| SCHEMBL11137376 | 0.83 | CPB2 (0.44) | CPB2ITGB3ITGA2BF2 | |
| SCHEMBL11133594 | 0.83 | CPB2 (0.50) | CPB2ITGB3ITGA2BF2PLG | |
| Hydrochloric Acid SCHEMBL9274562 | 0.83 | ADRB2 (0.47) | ADRB2ADRB1CYP4F2CYP4A11 | |
| SCHEMBL8421753 | 0.83 | PTGER2 (0.47) | PTGER2ADRB2ADRB1PTGER4PTGER3 | |
| SCHEMBL11134031 | 0.81 | CPB2 (0.48) | CPB2F2 | |
| SCHEMBL9453938 | 0.80 | PTGER2 (0.63) | PTGER2PTGER4PTGER3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-B1 | AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |
| US-4402975-A | ANTIULCER AGENTS | TEIJIN LIMITED (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0044541-A1 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds | TEIJIN LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |