Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132203 | 0.83 | HDAC8 (0.46) | THRATHRBHDAC1HDAC8DPP4 | |
| SCHEMBL11133284 | 0.82 | HDAC3 (0.54) | THRATHRBHDAC1HDAC8DPP4 | |
| SCHEMBL11134216 | 0.82 | HDAC3 (0.54) | THRATHRBHDAC1HDAC8DPP4 | |
| SCHEMBL11133258 | 0.82 | DPP4 (0.46) | THRATHRBHDAC1HDAC8DPP4 | |
| SCHEMBL11135374 | 0.82 | DPP4 (0.46) | THRATHRBHDAC1HDAC8DPP4 | |
| SCHEMBL11134102 | 0.82 | HDAC3 (0.54) | THRATHRBHDAC1HDAC8DPP4 | |
| SCHEMBL25944961 | 0.81 | HDAC2 (0.48) | HDAC1HDAC8MAPT | |
| Hydrochloric Acid SCHEMBL11134492 | 0.81 | HDAC3 (0.53) | THRATHRBHDAC1HDAC8DPP4 | |
| SCHEMBL11264047 | 0.80 | DPP4 (0.47) | THRATHRBDPP4HSD17B3L3MBTL1 | |
| SCHEMBL11134116 | 0.80 | L3MBTL1 (0.54) | THRBHDAC1HDAC8DPP4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-B1 | AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |
| EP-0044541-A1 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds | TEIJIN LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |