Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363260 | 0.83 | HSP90AB1 (0.49) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL9955458 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL9722805 | 0.71 | NR4A2 (0.47) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL11210238 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL3486575 | 0.67 | KDM4E (0.71) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL3575071 | 0.67 | MAPK1 (0.67) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL29059116 | 0.67 | ESR1 (0.67) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL11826284 | 0.67 | MAPK1 (0.65) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL10864591 | 0.67 | MAPK1 (0.65) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| SCHEMBL8956330 | 0.67 | MAPK1 (0.85) | SMN1; SMN2MAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58225017-A | — | — | None | — | — | JP | disclosed |
| JP-S58225017-A | AGENT FOR ELIMINATING CANCER | CHUGAI PHARMACEUT CO LTD | 1983-12-27 | — | — | JP | disclosed |