Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535484 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2PKMLMNATP53RAB9A | |
| SCHEMBL11134139 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMLMNATP53RAB9A | |
| SCHEMBL11134141 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMLMNATP53RAB9A | |
| SCHEMBL12180935 | 0.80 | CES2 (0.50) | SMN1; SMN2PKMLMNAPTGS1RAB9A | |
| SCHEMBL9706848 | 0.80 | CES2 (0.50) | SMN1; SMN2PKMLMNAPTGS1RAB9A | |
| SCHEMBL11329136 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2PKMLMNATP53RAB9A | |
| SCHEMBL11329134 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2PKMLMNATP53RAB9A | |
| SCHEMBL11135486 | 0.76 | KMT2A (0.46) | SMN1; SMN2PKMLMNATP53PTGS1 | |
| SCHEMBL11133433 | 0.76 | KMT2A (0.46) | SMN1; SMN2PKMLMNAPTGS1RAB9A | |
| SCHEMBL11520447 | 0.75 | CES2 (0.52) | SMN1; SMN2PKMLMNAPTGS1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399277-A | 7-Amino-3-phosphonocephalosporanic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |